Abstract
A detailed toxicity analysis was performed on the top minnow utilizing the stick‐enzyme immunoassay (S‐EIA), the mouse bioassay, the guinea pig atrium assay and fluorometric HPLC. The S‐EIA test indicated 96% of the samples tested contained polyether toxins. Mice injected with acetone extractions from top minnow displayed symptoms of toxicity while the guinea pig atrium assay demonstrated the presence of a polar, Na+ channel inhibitor.
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