Polyester Grafts Are a Risk Factor for Postimplantation Syndrome after Abdominal Endovascular Aneurysm Repair: Retrospective Analysis for Polyester Graft, Excluder®, and Endologix Powerlink®/AFX®.

Abstract

Objective: Postimplantation syndrome (PIS) is a postoperative syndrome that occurs after endovascular aneurysm repair (EVAR), accompanied by high fever, leukocytosis, and high serum C-reactive protein (CRP). Its pathogenesis and clinical meaning are still under discussion. Here, we evaluate the relationship between postoperative fever after EVAR and graft fabric focusing on Endologix Powerlink® and AFX® (EPL/AFX).Materials and Methods: From January 2015 to July 2017, data on elective EVAR for abdominal aortic aneurysm (AAA) using mainbody were retrospectively collected. The primary endpoint was maximal postoperative fever.Results: We identified 128 patients who underwent elective EVAR for AAA (105 males, 82%; aged 57–90, median: 74 years). The median maximal postoperative fever was 37.8°C (36.6–39.7°C): polyester graft, 38.2°C (37.1–39.7°C); Excluder®, 37.8°C (36.6–39.2°C); and EPL/AFX, 37.7°C (37–38.7°C). The maximal postoperative fever with a polyester graft was significantly higher than that with an expanded polytetrafluoroethylene (ePTFE) graft (p<0.001). However, there was no difference between Excluder® and EPL/AFX (p=0.214).Conclusion: In this study, it was found that polyester grafts are significantly associated with PIS after elective EVAR for AAA. If patient anatomy is permitted, it may be better to choose the ePTFE graft, especially for patients with a poor general condition.