Abstract
Background Improving the therapeutic index of drugs is a major impetus for innovation in many therapeutic areas such as HIV, cancer, inflammatory and other infectious diseases. Polyester based dendrimers constitute a very attractive class of materials because they are less toxic, biodegradable and biocompatible. Our aim is to develop a novel ester based versatile dendritic nanocarrier that could specifically deliver drugs against HIV, cancer and other infectious diseases.
Highlights
Improving the therapeutic index of drugs is a major impetus for innovation in many therapeutic areas such as HIV, cancer, inflammatory and other infectious diseases
The poly ester based dendrimeric nanocarrier was synthesized by using solid phase organic synthesis
Novel core-shell type polymer with surface specific amino functional groups was used for the nanocarrier synthesis
Summary
Improving the therapeutic index of drugs is a major impetus for innovation in many therapeutic areas such as HIV, cancer, inflammatory and other infectious diseases. Polyester based dendrimers constitute a very attractive class of materials because they are less toxic, biodegradable and biocompatible. Our aim is to develop a novel ester based versatile dendritic nanocarrier that could deliver drugs against HIV, cancer and other infectious diseases
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