Abstract
AbstractCell migration plays a crucial role in a variety of physiological and pathological processes. In this study a method of capillary force lithography was used to treat poly(sodium 4‐styrenesulfonate) (PSS)/poly(diallyldimethylammonium) chloride (PDADMAC) multilayers with a PDMS stamp before or after etching by NaCl solution, yielding physical patterns with various features such as double thin lines, double strips, meniscus‐shaped ridges, and high ridges. The ridge height is controllable in the range of 25 and 1100 nm. Migration of smooth muscle cells (SMCs) was restrained by the double‐line patterns in a ridge height‐dependent manner. By contrast, the mobility of SMCs was controlled by both the hydration ratio of the multilayers and the pattern features.
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