Abstract
Wound treatment is one of the key issues in current medical care and brings many troubles for the health system. It is critical to develop reliable and multifunctional materials for wound treatment. In this work, we prepared new gel microspheres loaded with basic fibroblast growth factor (bFGF) and coated with polydopamine (PDA) as wound dressing. The microspheres were prepared using microfluidic electrospray technology, and then treated with dopamine (DA) and bFGF solution. Owing to the loaded drug, the microspheres could promote the vascularization, while the PDA coating encapsulated the microspheres and prolonged the drug release process. Additionally, the microspheres have excellent biocompatibility, and can play a strongly active role in wound healing. These features indicate these microspheres are expected to be new dressing for wound healing.
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