Abstract
Heart plays an important role in blood circulation, and normal heart development is necessary for maintaining cardiac function. Therefore, the regulatory mechanisms underlying cardiac development are widely explored by scientists. Polycomb protein complexes are a group of protein which inhibits the transcription of related genes and regulates the expression of genes involved in the development of various tissues and organs. A better understanding of the molecular mechanism that controls heart development, coupled with an identification of novel roles of Polycomb, could provide the new insight for congenital heart diseases. Here, we mainly expound the relationship between the Polycomb protein complexes and heart development from the perspective of epigenetics.
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