Polychromatic Assessment of a Refractive Segmented EDOF Intraocular Lens.

Scott García,Luís Salvá,Salvador García-Delpech,Diego Montagud-Martínez,Anabel Martínez-Espert,Vicente Ferrando

doi:10.3390/jcm11061480

Abstract

This study aimed to evaluate in vitro performance refractive segmented EDOF intraocular lenses under polychromatic light using an optical bench that complies with the ISO 11979-2 Norm. The through focus modulation transfer function (TF-MTF) of the Femtis Comfort LS-313 MF15 (Oculentis GmbH, Berlin, Germany) IOL was evaluated for IOLs with three different base powers. The effect of the asymmetry of the segmented designs was evaluated with 3 different wavelengths and with polychromatic light at a 3.0 mm and 5.0 mm pupil diameter. It was demonstrated that the TF-MTF curves exhibit a bifocal profile that, in practice, results in an EDOF design. As a consequence of the LCA, the TF-MTF values in white light were lower than in monochromatic light. Images of the USAF test chart were obtained to confirm the prediction of the TF-MTFs. We found that Femtis Comfort is a bifocal low-addition IOL and this fact can result in an EDOF effect which was obtained previously in clinical trials. Moreover, we showed that the base power influences the IOL optical quality, which results as more effective for high powers (hyperopic eyes) than for low powers (myopic eyes). The LCA of the segmented refractive design was very low and presumably not clinically relevant.

Highlights

We studied the image quality provided by three oduiftfecroemntebsa. se power intraocular lenses (IOLs) for different wavelengths separately and with white light
To isolate polychromatic optical performance of the IOLs from the residual chromatic aberration generated by the optical elements in the optical bench, the optical setup was calibrated by measuring the LCA of the system without the IOL, and this result was subtracted from the experimental through focus modulation transfer function (TF-MTF) curves
We demonstrated that to the low Add value, the segmented bifocal design gives the lens its extended depth of focus (EDOF) character

Summary

Introduction

The surgical options for the correction of presbyopia have increased significantly in recent years. There are several types of EDOF IOLs with different optical designs, most of them based on diffractive optics. On the other ha2nodf ,9 most of the recent comparative studies of the optical properties of IOLs are made with lenses of different models and with similar base power [11,12,16], but there is a lack of objective ainncdideexnpceeroifmdeynstpahloitnofposrimasa[t4io–8n].abOonuethtyhpeoitnhfelsuisenfocre tohfisthgeooldenpseprfoowrmearnicne rceofuraldctbivee EDOF that, unlike what happens with diffractive designs in which chromatic aberration is a IcOritLicsa’l bpearhaamveioterr [u9n–1d3e]rinproelfyracchtirvoemdaetsiicgnislliut mis innoattsioonsi.gnInifictahnist, srienscpeeinctthtihsecapseoolynclyhromatic ptheerfAorbmbeaNncuemobfearnanIOd Litsdreesferravcteisveatitnednetxioinnflsuinecnecethites ibnechraevmioernut nindetrhepoploywcheror mofattihce lens is alicgchotm[1p4,a1n5]i.edHobwyeavneri,ntchreeraesies iinnsiutfsfitchieicnkt ninesvsitarondw/oorrkrwaditihi oreffrcaucrtvivaetumruelatifffoeccatlinlegnstehse optical ptoavthaliodfatleigthits ihnytpoothheesies.yOe.nItnhepoatrhteicruhlaanrd, ,tmo otshteofbtehset roecfeonut crokmnpoawralteivdegset,utdhiees cohf romatic ptheerfooprtmicalnpcreopfoertidesifofefrIeOnLtsbaaresempaodwe weristholefnasesseogfmdeifnfetreedntrmefordacetlisvaendIOwLithhasismnileavr er been obbasjeecptiovweelyr [s1t1u,1d2i,e1d6]., but there is a lack of objective and experimental information about the inIflnutehnicse wofotrhke lwenes hpaovweerpienrfroefrrmacetdivethEeDOfirFstIOcLosm’ bpeahraavtiivoreuenxdpeerrpimoleynchtarol mstautdicy of the cilhlurmominaattiiconb. T).hTe hfaer afanrdannedar nreefararcrtievferazcotniveseczaonnbeesclceaanrlybaepcplreeacrialytedapinprbeluceiaatnedd in blue ayneldloywe, lrleoswpe,crteivsepley.ctTihveesley.mTehaesuserems aeraesounrleysqauraeliotantilvyeqaunadliitnatteinvdeeadntdo sihnotewndtheedzotonaslhow the zpoonwaelrpdoiswtreibrudtiiosntrvibauritaitoionnvoafrtihaetiolennsodf ethsiegnle. ns design

Numerical Simulation

Optical Bench

Conclusions