Abstract

POLYARTERITIS NODOSA is a progressive and uniformly fatal disease. The classic picture is one of multisystem involvement with fever, polyneuritis, renal, dermal, and pulmonary involvement, and a chronic course. The following is a report of a patient with polyarteritis nodosa with widespread disease given long-term anticoagulant therapy. The improvement has been so marked on long-term anticoagulants that the report was felt to be justified. Report of a Case A 32-year-old engineer was admitted on May 22, 1960, to Presbyterian Hospital in Denver with acute onset of right upper quadrant pain associated with spiking fever and a tender, enlarged liver. The complete work-up yielded negative results except for a 4+ cephalin flocculation and test done with Rose Bengal I 131 which showed hepatic dysfunction compatible with hepatitis. There was no icterus. An exploratory laparotomy was performed on June 10, 1960, and a biopsy specimen of the liver disclosed subacute toxic hepatitis

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