Abstract
Vinylbenzyl chloride (VBC) was dispersion polymerized to give monodisperse microspheres in the presence of poly(vinylpyrrolidone) (PVP) as a steric stabilizer. The effect of PVP concentration on the size and on microsphere stability during the polymerization process was investigated. Microsphere size was examined when co-stabilizer molecules were employed with PVP during the polymerization reaction. The built-in reactive chloromethyl groups of the microspheres were the sites of the nucleophilic reaction of two amino-group model molecules, glucosamine (G), a hexosamine implicated in processes of molecular recognition, and also bovine serum albumin (BSA). Elemental analyses and Fourier transform infrared spectroscopy (FT IR) spectra showed that poly(vinylpyrrolidone) was associated with the microsphere network. Elemental analyses, attenuated total reflection infrared spectroscopy (AT RFT IR), and zeta potential measurements confirmed G and BSA links at the microsphere surface.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
