Poly (Terephthaloyl Diglyceride-co-1, 2-cyclohexanediacyl Diglyceride) - A Biodegradable and Biocompatible Functional Polymer for Biomedical Applications

Abstract

Biodegradable polyesters have been widely used in biomedical engineering. Introduction of functional groups to polyesters will expand their applications. Herein, we developed a functionalizable copolyester with free hydroxyl groups (-OH) - poly (terephthaloyl diglyceride-co-1,2-cyclohexanediacyl diglyceride) (PTeCD). PTeCD was readily synthesized by acid-induced epoxide ring-opening polymerization in one step. Its structure was characterized by NMR and FTIR. PTeCD exhibited a good cytocompatibility and biodegradability. We expect PTeCD will be a useful polymer for biomedical applications.