Poly (ether) sulfone electrospun nanofibrous membranes embedded with graphene oxide quantum dots with antimicrobial activity.

Abstract

This work describes the development of novel electrospun nanofibrous membranes (ENMs) prepared by embedding graphene oxide quantum dots (GOQDs) into poly (ether) sulfone (PES). FTIR and Raman spectroscopy confirmed the successful incorporation of the GOQDs into the PES membranes. The optimal electrospinning polymer concentration that showed no defects or bead formation was at 26wt% of the PES polymer. Spectroscopy, microscopy and contact angle were some of the techniques used to characterize the ENMs. SEM images showed smooth and unbranched ENMs. The average diameter upon incorporation of the GOQDs was determined to be 2.45μm. XRD revealed that theGOQDs werestructurally close to graphite with an interlaying space of 0.36nm. The antimicrobial effect of the GOQDs-PES electrospun nanofibrous membranes was assessed against three bacterial strains (Escherichia coli (E. coli), Staphylococcus aureus (S. aureus) and Bacillus cereus (B. cereus)) using the disc diffusion method. The electrospun nanofibres containing10wt% of GOQDs showed the most active antimicrobial activity against all three bacterial strains tested. The zones of inhibition ranged from 9 to 40mm. The minimum inhibitory concentration (MIC) was determined to be 0.5mg/mL, 0.3mg/mL and 0.2mg/mL for E. coli, B. cereus and S. aureus, respectively. The results demonstrated that incorporating GOQDs in the PES nanofibre gives rise to new antimicrobial properties, and as a result, the GOQDs-PES nanofibrous membrane can be used in antimicrobial applications such as water treatment.