Abstract
Allergic rhinitis (AR) is impacted by allergens and air pollution but interactions between air pollution, sleep and allergic diseases are insufficiently understood. POLLAR (Impact of air POLLution on sleep, Asthma and Rhinitis) is a project of the European Institute of Innovation and Technology (EIT Health). It will use a freely-existing application for AR monitoring that has been tested in 23 countries (the Allergy Diary, iOS and Android, 17,000 users, TLR8). The Allergy Diary will be combined with a new tool allowing queries on allergen, pollen (TLR2), sleep quality and disorders (TRL2) as well as existing longitudinal and geolocalized pollution data. Machine learning will be used to assess the relationship between air pollution, sleep and AR comparing polluted and non-polluted areas in 6 EU countries. Data generated in 2018 will be confirmed in 2019 and extended by the individual prospective assessment of pollution (portable sensor, TLR7) in AR. Sleep apnea patients will be used as a demonstrator of sleep disorder that can be modulated in terms of symptoms and severity by air pollution and AR. The geographic information system GIS will map the results. Consequences on quality of life (EQ-5D), asthma, school, work and sleep will be monitored and disseminated towards the population. The impacts of POLLAR will be (1) to propose novel care pathways integrating pollution, sleep and patients’ literacy, (2) to study sleep consequences of pollution and its impact on frequent chronic diseases, (3) to improve work productivity, (4) to propose the basis for a sentinel network at the EU level for pollution and allergy, (5) to assess the societal implications of the interaction. MASK paper N°32.
Highlights
Exposure to ambient air pollution increases morbidity and mortality
Mobile Airways Sentinel NetworK (MASK) should help to (i) understand the disease mechanisms and the effects of air pollution in allergic diseases, (ii) better appraise the burden incurred by medical needs and the indirect costs, (iii) propose novel multidisciplinary care pathways integrating pollution and patients’ literacy, (iv) improve work productivity, (v) propose the basis for a sentinel network at the European Union (EU) level for pollution and allergy and (vi) assess the societal implications of the project to reduce health and social inequalities globally
We have developed a new tool derived from Google Trends (GT) (TLR2) that will analyze all trends and that will be quantitative for allergen and pollution
Summary
Exposure to ambient air pollution increases morbidity and mortality. It is a leading contributor to global disease burden [1, 2]. POLLAR (Impact of Air POLLution on sleep, Asthma and Rhinitis) is a new project of the EIT Health that will embed environmental data into the Allergy Diary. MASK should help to (i) understand the disease mechanisms and the effects of air pollution in allergic diseases, (ii) better appraise the burden incurred by medical needs and the indirect costs, (iii) propose novel multidisciplinary care pathways integrating pollution and patients’ literacy, (iv) improve work productivity, (v) propose the basis for a sentinel network at the EU level for pollution and allergy and (vi) assess the societal implications of the project to reduce health and social inequalities globally. Test case implementation (Mo 1–12) We shall use the data from 4 countries with 20,000 users during the pollen season and analyse the interactions between air pollution, sleep and allergens
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