Abstract

BackgroundRecognising the substantial political weight of the United Nations General Assembly (UNGA), a UN General Assembly special session (UNGASS) and high-level meetings (HLMs) have been pursued and held for 5 health-related topics thus far. They have focused on human immunodeficiency virus/acquired immune deficiency syndrome (HIV/AIDS, 2001), non-communicable diseases (NCDs, 2011), antimicrobial resistance (AMR, 2016), tuberculosis (TB, 2018), and universal health coverage (UHC, 2019). This observational study presents a comprehensive analysis of the political and policy background that prompted the events, as well as an assessment of aims, approaches, and ultimate outcomes.Methods and findingsWe investigated relevant agencies’ official documents, performed a literature search, and accessed international institutions’ websites for the period 1990–2020. Knowledgeable diplomatic staff and experts provided additional information. Outcomes were evaluated from a United Nations perspective based on national and international commitments, and funding trends. Eliciting an effective governmental response through UNGASSs/HLMs is a challenge. However, increased international commitment was evident after the HIV/AIDS (2001), NCDs (2011), and AMR (2016) meetings. The more recent TB (2018) and UHC (2019) HLMs have received general endorsements internationally, although concrete commitments are not yet documented. Although attribution can only be hypothesized, financial investments for HIV/AIDS following the UNGASS were remarkable, whereas following HLMs for NCDs, AMR, and TB, the financial investments remained insufficient to face the burden of these threats. Thus far, the HIV/AIDS UNGASS was the only one followed by a level of commitment that has likely contributed to the reversal of the previous burden trend. Limitations of this study include its global perspective and aerial view that cannot discern the effects at the country level. Additionally, possible peculiarities that modified the response to the meetings were not looked at in detail. Finally, we assessed a small sample of events; thus, the list of strategic characteristics for success is not exhaustive.ConclusionsOverall, UNGASSs and HLMs have the potential to lay better foundations and boldly address key health challenges. However, to succeed, they need to (i) be backed by large consensus; (ii) engage UN authorities and high-level bodies; (iii) emphasise implications for international security and the world economy; (iv) be supported by the civil society, activists, and champions; and (v) produce a political declaration containing specific, measurable, achievable, relevant, and time-bound (SMART) targets. Therefore, to ensure impact on health challenges, in addition to working with the World Health Assembly and health ministries, engaging the higher political level represented by the UNGA and heads of state and government is critical.

Highlights

  • The United Nations General Assembly (UNGA) carries a weight that is politically greater than that of any international health-related body worldwide, including the World Health Assembly (WHA) of the World Health Organization (WHO) [1]

  • To ensure impact on health challenges, in addition to working with the World Health Assembly and health ministries, engaging the higher political level represented by the UNGA and heads of state and government is critical

  • Four key factors were involved in the promotion of the HIV/AIDS topic to the UNGA in 2001: the extensive work of awareness-raising and advocacy by United Nations Programme on HIV/AIDS (UNAIDS), the personal commitments of the UN Secretary-General, the unprecedented inclusion of a health-related topic in the agenda of the UN Security Council, and the strong activism by a civil society that was fighting in response to the HIV epidemic and for the rights of lesbian, gay, bisexual, transgender, questioning, and intersex (LGBTQI) communities as well as those of ethnic minorities especially vulnerable to HIV/AIDS [33,34]

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Summary

Introduction

The United Nations General Assembly (UNGA) carries a weight that is politically greater than that of any international health-related body worldwide, including the World Health Assembly (WHA) of the World Health Organization (WHO) [1]. Since 2001, 5 pivotal meetings on global health challenges have taken place at the United Nations (UN) in the form of either UNGA special session (UNGASS) or high-level meeting (HLM) They focused on human immunodeficiency virus/acquired immune deficiency syndrome (HIV/AIDS) in 2001 [2], with follow-up HLMs in 2006 [3], 2011 [4], and 2016 [5]; non-communicable diseases (NCDs) in 2011 [6], with follow-up HLMs in 2014 [7] and 2018 [8]A; aUnt:imRiecfr1⁄2o8b wiaal srGesriostuapnocfe8(:ADMecRla)riantionofG8Su 2016 [9]; tuberculosis (TB) in 2018 [10]; and universal health coverage (UHC) in 2019 [11]. Recognising the sAuUbs: tPalnetaiasel cphoelcitkicthaal twtheeiegdhitsotof theeseUnnteitnecde}NRaetcioongsniGzinegn:e::r}aclaApstusreemyobulrymeaning:Ifnot; plea (UNGA), a UN General Assembly special session (UNGASS) and high-level meetings (HLMs) have been pursued and held for 5 health-related topics far They have focused on human immunodeficiency virus/acquired immune deficiency syndrome (HIV/AIDS, 2001), non-communicable diseases (NCDs, 2011), antimicrobial resistance (AMR, 2016), tuberculosis (TB, 2018), and universal health coverage (UHC, 2019). This observational study presents a comprehensive analysis of the political and policy background that prompted the events, as well as an assessment of aims, approaches, and ultimate outcomes

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