POLIMORFISME GEN ALPHA ACTININ-3 (ACTN 3) BERHUBUNGAN DENGAN MUSCLE PERFOMANCE ATLET

Nila Wahyuni

doi:10.24843/spj.2019.v07.i03.p03

Abstract

Background: The performance of professional athletes is very important for the achievement of athletes. The athlete's performance is influenced by various factors, namely environmental factors such as training, diet and sociocultural. One important factor that also affects the performance of athletes is genetic factor that are currently being studied. One of the genetic factors believed to play a role in athlete's performance is the Alpha Actinin-3 gene (ACTN 3). Purpose : to examine how the Alpha Actinin-3 (ACTN 3) gene polymorphism causes variation among individuals in athletic muscle performance. Method : study literature. Result : The ACTN 3 gene codes for the ?-actinin-3 protein which plays a role in producing a large force of contraction (rapid forceful contraction). The genetic variation of the ACTN 3 gene causes several variants of the ACTN 3 gene that play a role in the athlete's muscle performance.Keywords: Polymorphism, ACTN Gen 3, Muscle performance.

Highlights

The performance of professional athletes is very important for the achievement of athletes
The athlete's performance is influenced by various factors
One important factor that also affects the performance of athletes is genetic factor

Summary

Introduction

The performance of professional athletes is very important for the achievement of athletes. Berdasarkan hasil metanalisis pada 88 artikel oleh Ma et al tahun 2103 disimpulkan bahwa polimorfisme gen ACTN 3 yaitu ACTN 3 allelle R berhubungan signifikan dengan muscle power performance atlet sedangkan gen ACTN3 genotip XX berperan dalam muscle endurance atlet[5]. Hasil penelitian tersebut sejalan dengan penelitian oleh Orysiak, J tahun 2014 menemukan bahwa polimorfisme gen ACTN 3 R577X berhubungan signifikan dengan kemampuan atlet muda pria dalam menghasilkan daya ledak otot pada ekstremitas bawah[7].

Results

Conclusion