Abstract
In a literature review the theoretical fundamentals and achievements in osseous implants' investigations have been presented. Especially polymeric materials used in implants were discussed as well as the criteria of the proper polymers choice. These criteria cover the structure of a polymer, porosity, mechanical and surface properties and biodegradation process course. Modification of osseous implant surface with proteins has been also discussed. The part concerning the own research contains the results of evaluation of bone cells' (osteoblasts) adhesion to various types of biomaterials, used as porous osseous implants. A new way of evaluation, presented in Scheme A, was used. Contact angle values (CA, Fig. 1) of the surfaces obtained were measured. Also viability of cells after one-week incubation was investigated basing on the measurements of activity of enzymes of succinate dehydrogenase (XTT Test, Fig. 2) or alkaline phosphatase (ALP Test, Fig. 3). 11 series of measurements differing in the substrate type were done. The best results have been obtained for the surfaces with dextran as well as with the systems: dextran + poly(acrylic acid) (PAA), dextran + Ca(NO3)2 or dextran + PAA + Ca(NO3)2. We did not find an unambiguous correlation between biological tests results and hydrophylic or hydrophobic character of polymeric substrate.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
