Polikistik Over Sendromu ve Uyku Bozuklukları: Uyku Bileşenleri ile Metabolik ve Androjenik Bozukluklar Arasındaki İlişki

Abstract

Objective: To investigate the sleep quality in patients with polycystic ovary syndrome (PCOS) and to examine the effects of metabolic parameters on sleep disturbances.
 Material and Methods: The study included 50 patients diagnosed as PCOS and 51 normal healthy volunteers. The Pittsburgh Sleep Quality Index (PSQI) was used to evaluate the sleep quality. Index consists of 18 items and seven components and according to the index, the total scores of five or more indicate a poor sleep quality. After the sleep quality scores were determined, serum insulin, triglyceride, cholesterol, fasting glucose and androgen levels were recorded retrospectively and all parameters compared between groups.
 Results: The sleep quality was lower in the patients with polycystic ovary syndrome than in the healthy control group but this was not statistically significant (p>0.05). Serum dehydroepiandrosterone sulfate (DHESO4) and total testosterone level had a significant negative correlation with sleep duration and total
 PSQI scores. In addition, serum total testosterone level also had a significant negative correlation with sleep latency, sleep disturbance and subjective sleep quality. Besides, the patients with the poor sleep quality had significantly lower serum dehydroepiandrosterone sulfate and testosterone levels than those with a normal sleep quality (p