Abstract
A polarization sensitive endoscopic optical frequency domain imaging (PS-OFDI) system with a motorized distal scanning catheter is demonstrated. It employs a passive polarization delay unit to multiplex two orthogonal probing polarization states in depth, and a polarization diverse detection unit to detect interference signal in two orthogonal polarization channels. Per depth location four electro-magnetic field components are measured that can be represented in a complex 2x2 field matrix. A Jones matrix of the sample is derived and the sample birefringence is extracted by eigenvalue decomposition. The condition of balanced detection and the polarization mode dispersion are quantified. A complex field averaging method based on the alignment of randomly pointing field phasors is developed to reduce speckle noise. The variation of the polarization states incident on the tissue due to the circular scanning and catheter sheath birefringence is investigated. With this system we demonstrated imaging of ex vivo chicken muscle, in vivo pig lung and ex vivo human lung specimens.
Highlights
Optical coherence tomography (OCT) is an optical imaging technique which can acquire noninvasive high resolution cross sectional images in real time [1]
The variation of the polarization states incident on the tissue due to the circular scanning and catheter sheath birefringence is investigated. With this system we demonstrated imaging of ex vivo chicken muscle, in vivo pig lung and ex vivo human lung specimens
In this paper we demonstrate a polarization sensitive endoscopic optical frequency domain imaging (OFDI) system with a distal scanning miniature catheter
Summary
Optical coherence tomography (OCT) is an optical imaging technique which can acquire noninvasive high resolution cross sectional images in real time [1]. In this paper we demonstrate a polarization sensitive endoscopic optical frequency domain imaging (OFDI) system with a distal scanning miniature catheter. Structural and Jones matrix based phase retardation images are acquired of ex vivo chicken sample, in vivo pig lung and ex vivo human lung specimens Technical issues such as complex field averaging and polarization state stability are discussed in depth. A passive polarization delay unit (PDU) similar to those reported by [29, 30] is added to the sample arm to multiplex two orthogonal incident polarization states in depth. The wavelength-dependent splitting ratio of the micro-optic assembly is low, allowing for balanced-detection at relative high reference arm powers (Fig. 2). Connect the catheter into the sample arm, control the polarization controller before the PDU to equalize the power going into the two orthogonal incident states. A home-made motor driver drives the scanning at 3120 rpm, i.e. the B-scan rate is 52 fps
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