Polar Constituents from Sageretia Thea Leaf Characterized by HPLC‐SPE‐NMR Assisted Approaches

Abstract

AbstractNine glycosides (1–9) were characterized from the n‐butanol‐soluble fraction of the ethanolic extract of the leaves of Sageretia thea by the general approach. Among these, Compounds 6 and 7 were identified as a mixture. Application of HPLC‐SPE‐NMR in two selected fractions led to the separation of this mixture and the characterization of three additional minors (10–12). Among these, 7‐O‐methylmyricetin 3‐O‐α‐l‐arabinofuranoside (8) is a new natural product and eight compounds, i.e. glucofragulin A (1), quercetin‐3‐O‐α‐l‐arabinopyranoside (5), 3‐O‐β‐d‐galactopyranoside (6), 3‐O‐β‐d‐glucopyranoside (7), and 3‐O‐α‐l‐arabinofuranoside (11), myricetin‐3‐O‐α‐l‐arabinofuranoside (9) and 3‐O‐β‐d‐glucopyranoside (10), and quercetrin (12), are found for the first time from the title plant.