Abstract
This research aimed to analyze the insulin and ACE Inhibitor therapy to patients with DM type 2 with hypertension, and giving a picture about the influence on the blood sugar control and blood pressure using the parameter of fasting blood glucose, HbA1C, and blood pressure. The research was conducted in the endocrine clinic of DR. Wahidin Sudirohusodo General Hospital, Makassar, from 2 May through 12 July, 2016. The research was a Cross-Sectional study with the samples chosen using the evhaustive sampling technique. The types of insulin and antihypertension class ACE inhibitor as revealed by the interviews with the patients. The therapy effects of pre and post interventions were analyzed using the parameter of glycemia, and HbA1C using the pair sample T-test and blood pressure using Wilcoxon test. The research results indicated that the level of blood sugar after fasting was reduced to 64.08 and the level of HbA1C was reduced to 1.51 with the value of P = 0.000. The parameter of systolic and diastolic blood pressures had equal degradation of 12.56 and 12.32 respectively with value of P = 0.000, meaning P<0.05 in statistics.
Highlights
Abstrak: The research aimed to analyze the insulin and ACE Inhibitor therapy in patients with Diabetes melitus (DM) type 2 with hypertension, and giving a profile about the influence on the blood sugar control and blood pressure using the parameter of fasting blood glucose, HbA1C, and blood pressure
The types of insulin and antihypertension class ACE inhibitor was revealed by the interviews with the patients
The therapy effects of pre and post interventions were analyzed using the parameter of glycaemia, and HbA1C using the pair sample T-test and blood pressure using Wilcoxon test
Summary
Tabel 2 menunjukkan bahwa untuk terapi insulin, frekuensi penggunaan terapi kombinasi lebih tinggi, yaitu 20 orang (80%) dibandingkan dengan terapi tunggal, yaitu 5 0rang (20%). Pilihan jenis insulin untuk terapi tunggal, hampir sama frekuensinya antara. Insulin untuk terapi kombinasi semua sampel menggunakan kombinasi Novorapid denganLevemir. Sementara untuk terapi ACE inhibitor, frekuensi penggunaan terapi tunggal hampir sama dengan terapi kombinasi, yaitu 13 orang (52%) sementara terapi kombinasi sebanyak 12 orang (48%). Pilihan jenis untuk terapi tunggal ACE Inhibitor yang tertinggi adalah captopril, 12,5 mg sebanyak 5 orang (20%) dan Ramipril 2.5 mg, yaitu 4 orang (16%). Pilihan terapi dengan frekuensi tertinggi untuk kombinasi ACE inhibitor dengan 2 jenis obat adalah Ramipril 2.5 mg dan Bisoprolol 2,5 mg yaitu 4 orang (26%) sementara. ACE inhibitor dengan kombinasi 3 obat memiliki frekuensi yang sama
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