Abstract
Introduction: Colchicine, which is derived from a herb called Colchicum is a medication used to treat gout. Colchicum itself can act as a deadly toxic herb in the case of over dose. This is a case report study which investigates a patient who was poisoned with Colchicum (Soranjan, what it is called in Iran). Description: The patient was a 44-year-old man who came to the emergency poisoning ward after a day of mountaineering and eating Soup. He had severe nausea and vomiting. The patient was admitted to the ICU two days later with a toxic general condition, complaining of chest pain, nausea, vomiting and shortness of breath. The patient lab tests showed elevated liver enzymes and pancytopenia. The patient respiratory distress developed and physician had to intubate the patient. The patient was treated with antibiotics, GCSF for pancytopenia and antioxidant to protect the liver. Conclusion: The patient responded to broad spectrum antibiotic, antifungal and GCSF. paying attention to the patient’s history was the key of success to diagnosis.
Highlights
Colchicine, which is derived from a herb called Colchicum is a medication used to treat gout
We report a patient with an herbal medicine containing colchicine called Soranjan
Finkelstein and et al showed Colchicine poisoning presents in three usually overlapping phases: 1) 10-24 h after ingestion is considered as the gastrointestinal phase which mimicks gastroenteritis
Summary
Colchicine is a well-known medication for the treatment of gout and fever, whose treatment and toxicity spectrum is unknown. Colchicum speciosumis (figure 1) a species of flowering plant in the family Colchicaceae, native to mountainous areas of northern Turkey, the Caucasus and northern Iran
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