Abstract

Background: Peripheral perfusion assessment is used routinely at the bedside by measuring the capillary refill time (CRT). Recent clinical trials have shown evidence to its ability to recognize conditions with decreased end organ perfusion as well as guiding therapeutic interventions in sepsis. However, the current standard of physician assessment at the bedside has shown large variability. New technology can improve the precision and repeatability of CRT affecting translation of previous high impact research.Methods: This was a prospective, observational study in the intensive care unit and emergency department at a quaternary care hospital using a non-invasive finger sensor for CRT. The device CRT was compared to the gold standard of trained research personnel assessment of CRT as well as to providers clinically caring for the patient.Results: Pearson correlations coefficients were performed across 89 pairs of measurements. The Pearson correlation for the device CRT compared to research personnel CRT was 0.693. The Pearson correlation for the provider CRT compared to research personnel CRT was 0.359.Conclusions: New point-of-care technology shows great promise in the ability to improve peripheral perfusion assessment performed at the bedside in the emergency department triage and during active resuscitation. This standardized approach allows for better translation of prior research that is limited by the subjectivity of manual visual assessment of CRT.

Highlights

  • 1 million patients present annually to United States emergency departments with sepsis [1]

  • One measure that has been used in clinical practice for decades as a marker of perfusion is capillary refill time (CRT)

  • The intensive care unit (ICU) consisted of 25 patients with an average age of 58.5 years and 40% male

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Summary

Introduction

1 million patients present annually to United States emergency departments with sepsis [1]. The mortal consequences of delayed diagnosis creates an imperative for improved early identification and intervention to meet the Surviving Sepsis goals of therapy. One measure that has been used in clinical practice for decades as a marker of perfusion is capillary refill time (CRT). There is a great deal of subjectivity and variability in how providers apply and interpret results of this simple, non-specific marker of oxygen delivery [3]. Technology can standardize this measurement making it objective, reproducible and precise. Peripheral perfusion assessment is used routinely at the bedside by measuring the capillary refill time (CRT). New technology can improve the precision and repeatability of CRT affecting translation of previous high impact research

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