Abstract
There are many disorders in which cyanocobalamin therapy has been tried, but in none has benefit been demonstrated by suitably controlled studies unless a deficiency of the vita¬ min has also been found. Doses have usually been massive (l,000ug by injection, weekly, daily, even three times a day). It is used to treat all kinds of anemia. Anemia does not im¬ prove because of such therapy if there is no vitamin B12 deficiency. Con¬ trolled studies have failed to demon¬
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