Abstract
Podocyturia as a biomarker of early kidney damage in fabry nephropathy
Highlights
Glomerular involvement is invariably present in the progression of kidney disease, regardless of the etiology under consideration
Podocytes are lost in the urine, a phenomenon known as podocyturia
This podocyte loss precedes the appearance of proteinuria, another marker of kidney disease
Summary
Glomerular involvement is invariably present in the progression of kidney disease, regardless of the etiology under consideration. *Correspondence: Hernán Trimarchi, Nephrology Service, Hospital Británico de Buenos Aires, Perdriel 74 (1280) Buenos Aires, Argentina. This podocyte loss precedes the appearance of proteinuria, another marker of kidney disease. The identification of a podocyte loss above normal levels in patients with normal renal function and without proteinuria may alert physicians to investigate a probable glomerular involvement at early subclincal stages.
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