Abstract

The use of targeted molecular therapies (TMT) such as bevacizumab, sunitinib, and sorafenib prior to cytoreductive nephrectomy (CN) holds promise as a rational treatment paradigm for patients with metastatic renal cell carcinoma (mRCC). To analyze their safety in pre-surgical setting, we evaluated surgical parameters and perioperative complications in patients treated with TMTs prior to CN and compared them to a matched patient cohort who underwent initial CN.

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