Abstract

Acute kidney injury (AKI) is a significant problem for patients admitted to the intensive care unit (ICU), both due to the high incidence and associated mortality with rates of AKI requiring renal replacement therapy (RRT) of over 5%, and mortality rates with AKI of over 60% 1, 2.Ultrasound can be used to identify those at risk for AKI and assist with AKI management. Risk factors for AKI in the ICU not only include hypoperfusion but also venous congestion and volume overload. Volume overload and vascular congestion are associated with multi-organ dysfunction and worse renal outcomes. Daily and overall fluid balance, daily weights, and physical examination for edema can be inaccurate and belie true systemic venous pressure 3, 4, 5. Bedside ultrasound allows providers to evaluate vascular flow patterns and obtain a more reliable evaluation of volume status to guide and individualize therapies. Cardiac, lung, and vascular patterns on ultrasound can identify preload responsiveness, which should be assessed to safely manage ongoing fluid resuscitation and assess for signs of fluid intolerance. Here we present an overview in the use of point of care ultrasound with particular emphasis on nephro-centric strategies, namely in the identification of the type of renal injury, renal vascular flow assessment, the static measure of volume status, as well as dynamic evaluation for volume optimization in critically ill patients.

Highlights

  • Acute kidney injury is a pervasive issue for patients admitted to the intensive care unit (ICU)

  • Bedside ultrasound assists with determining the etiology for Acute kidney injury (AKI) and allows providers to evaluate vascular flow patterns to obtain a reliable evaluation of volume status and guide individualized therapies to help improve renal outcomes

  • If hyperdynamism is visualized, performing a left ventricular outflow tract (LVOT) velocity time integral (VTI) measurement can help distinguish between hypovolemia and vasoplegia

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Summary

Introduction

Acute kidney injury (AKI) is a significant problem for patients admitted to the intensive care unit (ICU), both due to the high incidence and associated mortality with rates of AKI requiring renal replacement therapy (RRT) of over 5%, and mortality rates with AKI of over 60% [1,2]. Bedside ultrasound assists with determining the etiology for AKI and allows providers to evaluate vascular flow patterns to obtain a reliable evaluation of volume status and guide individualized therapies to help improve renal outcomes. Many of these dynamic measures used to evaluate for fluid responsiveness rely on heart-lung interactions during mechanical ventilation and involve the use of ultrasound.

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