PO-706-05 DECREASE IN ACTIVITY OF DAILY LIVING DURING THE COVID-19 PANDEMIC CORRELATES WITH A DECREASE IN BIOMETRIC VARIABLES

Abstract

The COVID-19 pandemic caused home quarantine of majority of US population including patients with CIED. Outpatient remote monitoring can be used to record and analyze basic biometric variables during the months of the pandemic. To compare the biometric variables as heart rate and heart rate variability with daily physical activity before and during COVID-19 pandemic in patients with CIED. We retrospectively analyzed CareLinkTM data transmissions across a large healthcare system prior and during the COVID-19 pandemic. The cohort included 345,459 transmissions from 4141 patients between March and May in 2019 and 464,003 transmissions from 5371 patients in 2020. When comparing the period of March to May of 2019 to March to May of 2020 there was a significant decrease in daily physical activity (244±153 min vs. 204±143 min; p< 0.0001), decrease in day-time average HR (75.3± 9 bpm vs. 74.4±9 bpm; p< 0.0001), decrease in night-time average HR (69.0±8.8 bpm vs. 68.2±8.7 bpm; p< 0.0001) and decrease HR variability (81.5±30.4 ms vs. 80.2±34.2 ms ; p< 0.0001). During March and May of 2020 there was a significant correlation between the daily physical activity and HR variability (r2=0.24; p < 0.0001), day-time HR (r2=0.32; p < 0.0001) and night-time HR (r2=0.02; p < 0.0001). During the COVID-19 pandemic there was a significant decrease in the daily physical activity in patients with CIED likely from home quarantine that correlated with a decrease in HR variability, day-time HR and night-time HR. The changes in these parameters may adversely affect overall cardiovascular health and outcomes of patients with CIED.