Abstract
The treadmill exercise stress test (TEST) can unmask concealed long QT syndrome (LQTS), especially LQT1, by identifying a maladaptive QT response during the TEST’s recovery phase. Additionally, the supine-stand test may aid in LQTS diagnosis as patients fail to shorten their QT interval in response to standing up, and instead show a paradoxical increase of QT. However, as the supine-stand test protocol requires patients to be supine and then standing for ≥ 5 minutes, this often does not match the standard TEST protocols and as such, the clinical utility needs to be validated.
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