Abstract
Post-traumatic stress disorder (PTSD) is prevalent among veteran populations and is frequently unyielding to current evidence-based therapies, leading to a high incidence of severe treatment-resistant PTSD (TRPTSD)1,2. Deep brain stimulation offers precision, long-term application, and ongoing adjustability3. The aim of this current study (Clinicaltrials.gov NCT04152993) is to use responsive neurostimulation, targeting clinical symptoms based on simultaneously recorded alterations in fear circuitry in TRPTSD.
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