Abstract
Epidural spinal cord stimulation (SCS) for the treatment of pain has seen tremendous growth and development over the last decade (1). Novel techniques such as burst stimulation, high-frequency stimulation, pulse-width (PW) variation, and differential targeting have provided new treatment options for those suffering from chronic pain(2, 3). However, these variations in stimulation parameters are likely providing treatment by different mechanisms. Each treatment paradigm likely introduces different electrical dosing in different areas of the spinal cord depending on these stimulation parameters.
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