Abstract

Diagnosis of hypertrophic cardiomyopathy (HCM) has far-reaching clinical implications. The gold standard non-invasive test for diagnosing HCM is cardiac MRI (CMR), but this is expensive and not readily available. Standard ECG measures of left ventricular hypertrophy may not differentiate HCM from other more benign causes of cardiac hypertrophy. The spatial ventricular gradient (SVG), a vectorcardiographic measure of global electrical heterogeneity (GEH), reflects global abnormalities in cardiac depolarization and repolarization, and may be able to distinguish HCM from other disorders.

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