PO-650-08 VALUE OF ATROPINE TEST TO ESTIMATE THE CARDIONEUROABLATION RESULT

Abstract

Vagal innervation keeps an autonomic tone that predominates most of the time. Because of this, the isolated sinus heart rate (HR) is higher than the in-situ sinus rate. Atropine stops vagal action by blocking muscarinic receptors in the heart. Several studies have shown that cardioneuroablation (CNA) also promotes blocking of vagal action by partially eliminating the postganglionic parasympathetic neuron. Thus, when CNA is performed, there is typically an increase in HR. Previously knowing whether HR will increase with CNA is critical information since CNA is not indicated if there is no atropine response.