PO-05-193 PREVALENCE OF ARRHYTHMIAS AND CARDIAC CONDUCTION DISEASE IN PATIENTS WITH LEFT VENTRICULAR ASSIST DEVICE

Abstract

Left ventricular assist devices (LVADs) have been shown to increase the functional status and survival of patients with end -stage heart failure. There is limited data regarding the prevalence of arrhythmias and conduction disease in patients implanted with LVADs. Our objective was to determine the prevalence of arrhythmias and conduction disease in hospitalized patients with LVADs using the National Inpatient Sample (NIS) from 2016-2019. A retrospective study was done using the Nationwide Inpatient Sample from 2016-2019. 17,125 hospitalisations with LVADs were identified using ICD-10 codes. Multivariate logistic regression analysis was used to adjust for confounders and analyze the variables for the adjusted odds ratio. Among 17,125 hospitalizations, the average age was 55 years and 62% were male. Atrial fibrillation (AF) was the most prevalent (43%) atrial arrhythmia, followed by atrial flutter (AFL) (14%), and supraventricular tachycardia (SVT) (13%). Ventricular tachycardia (VT) was the most common ventricular arrhythmia (47%), and less than one percent of the cohort had reported episodes of ventricular fibrillation/flutter (< 1%). In terms of conduction disease, 10% had either first-degree (1AVB), <1% had second-degree AV block (2AVB), 10% had right (RBBB), and 3% had left bundle branch block (LBBB). When adjusted to patient demographics, comorbidities, and hospital characteristics, patients with LVADs had a higher risk of AF (aOR= 2.00, p<0.0001), AFL (aOR=3.5, p<0.0001), SVT (aOR=4.63, p<0.0001), VT (aOR=17.7, p<0.0001), and complete heart block (CHB) (aOR=2.6, p<0.0001). Patients with LVADs are more likely to develop atrial fibrillation, atrial flutter, supraventricular tachycardia, ventricular tachycardia, RBBB, and CHB. Atrial fibrillation was our cohort's most common arrhythmia, consistent with prior observational studies' trends.