PO-05-072 IN-HOSPITAL OUTCOMES OF VENTRICULAR TACHYCARDIA ABLATION IN OCTOGENARIANS: A NATIONWIDE INPATIENT SAMPLE ANALYSIS

Abstract

Data on in-hospital outcomes of octogenarians undergoing ventricular tachycardia (VT) ablation are limited. We aimed to study the in-hospital outcomes of octogenarians undergoing VT ablation in the United States. We utilized the Nationwide Inpatient Sample (NIS) from 2016-2019 to identify the patients undergoing VT ablation. Octogenarians were defined as individuals aged ≥80 years.Primary outcome was in-hospital mortality. Secondary outcomes were acute kidney injury (AKI), new requirement of dialysis, cardiac tamponade, blood transfusion, and vascular complications. Multivariate logistic regression was used to adjust for baseline patient and hospital characteristics. 34,425 hospitalizations for VT ablation were identified, of which 3,890 (11.3%) were performed in octogenarians. Octogenarians undergoing VT ablation were more likely to be Caucasians (89.6% vs. 78.3%, P<0.01) and had a significantly higher burden of comorbidities with increased prevalence of heart failure, peripheral vascular disease, coronary artery disease, and stroke as compared with non-octogenarians. After adjustment for baseline patient and hospital characteristics, there were no significant differences in in-hospital mortality [adjusted odds ratio (aOR): 1.19 (95% CI, 0.79-1.79), p=0.39], AKI (aOR: 1.01 (95% CI, 0.84-1.22), P=0.89), blood transfusion (aOR: 1.43 (95% CI, 0.99-2.04), P=0.05), cardiac tamponade (aOR: 0.61 (95% CI, 0.29-1.27), P=0.19), and vascular complications (aOR: 0.94 (95% CI, 0.54-1.62), P=0.82) between octogenarians versus non-octogenarians. The in-hospital outcomes of octogenarians undergoing VT ablation are similar to non-octogenarians. These data suggest that VT ablation has similar safety profile in elderly versus younger patient populations.