PO-05-046 TRENDS IN NON-INFECTIOUS CARDIOVASCULAR IMPLANTABLE ELECTRONIC DEVICE COMPLICATIONS OVER THIRTY YEARS: INSIGHTS FROM THE ROCHESTER EPIDEMIOLOGY PROJECT DEVICE REGISTRY

Abstract

Cardiovascular implantable electronic devices (CIEDs) such as permanent pacemakers, implantable cardioverter-defibrillators, and cardiac resynchronization therapy devices alleviate morbidity and mortality in various diseases. There is a paucity of real-world data on CIED complications and trends. Describe trends in non-infectious CIED complications over the past three decades in Olmsted County. The Rochester Epidemiology Project is a medical records linkage system comprising records of over 500,000 residents of Olmsted County from 1966-current. CIED implants between 1988-2018 were determined. Trends in non-infectious complications within 30 days of implant were analyzed. A total of 194 complications were noted in 2536 patients. Lead dislodgement was the most common (3.0%), followed by hematoma (2.1%). Complications went up from 1988 to 2005, then showed a downtrend until 2018, driven by a decline in hematomas in the last decade (p<0.01). Those with complications were noted to have more valvular disease and greater mortality. The Charlson comorbidity score went up until 2011 and then trended down. Trends for specific complications are elucidated in the Figure. Our study describes a real-world trend of CIED complications over three decades. Lead dislodgements and hematomas were the most common complications. Complications have declined over the last decade, likely owing to safer practices and better understanding of anticoagulant management.