PO-01-066 IMPACT OF THE MORPHOLOGY-VOLTAGE-P-WAVE DURATION SCORE ON THE OUTCOME OF CATHETER ABLATION OF PERSISTENT ATRIAL FIBRILLATION

Abstract

The morphology-Voltage-P-wave duration (MVP) score, a score composed of three p-wave variables, is associated with new-onset atrial fibrillation (AF). An association between the MVP score and outcomes of catheter ablation (CA) of persistent AF has not been established. This study aimed to evaluate the predictive value of the MVP score on AF recurrence after CA in patients with persistent AF. One hundred fifty-eight consecutive patients (64.4±11.6 years, 116 male) receiving CA of persistent AF were enrolled. Pharmacological or electrical cardioversion was performed before CA in all patients, and the MVP score was calculated based on the p-wave morphology in the inferior leads, peak voltage in lead I, and p-wave duration on electrocardiography during sinus rhythm. Each variable could be assigned a weight of 0, 1, or 2 points and the total score was calculated. Univariate and multivariate analyses using a Cox proportional hazard model were carried out to determine the factors predicting late recurrence of AF (LRAF), which meant AF recurrence later than 3 months post-CA. During a follow-up of 31.9±18.8 months, 41 patients (26.1%) experienced LRAFs. The MVP score was significantly higher in LRAF patients than in those without LRAF (4.0 [2.0-5.0] versus. 2.0 [2.0-2.0], p<0.001)]. In the univariate analysis, the MVP score, age, left atrial dimension, and brain natriuretic peptide level were related to LRAFs. A multivariate analysis found that a higher MVP score was a significant predictive factor of LRAFs (hazard ratio: 2.12, 95% confidence interval: 1.72-2.65, p<0.001). This study revealed that the MVP score could predict LRAFs post-CA in persistent AF patients.