Abstract
Letters15 August 1991Pneumothorax in AIDSCharles A. Kennedy, MDCharles A. Kennedy, MDSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-115-4-328_2 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the Editors:In a 9-year longitudinal study by Sepkowitz and colleagues, spontaneous pneumothorax developed in 20 of 1030 (2.0%) patients with the acquired immunodeficiency syndrome (AIDS) (1). The relative risk for pneumothorax was associated with prophylactic aerosolized pentamidine and previous episodes ofPneumocystis cariniipneumonia (1). Patients were initially randomized to receive 30, 45, or 60 mg of aerosolized pentamidine every 2 weeks using a Seimens microinhalation device (Seimens Corporation, Munich, Germany). Subsequently, all patients received 60 mg of aerosolized pentamidine using a different nebulizing device (Fisoneb, Fisons Pharmaceuticals, Rochester, New York). The authors do not provide specific...
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