Abstract
Background Common Variable Immunodeficiency (CVID) is a Primary Immunodeficiency characterized by an association of IgG deficiency with IgA and/or IgM deficiency, and a decrease in the function of specific antibodies, discarding other causes of hipogamaglobulinemia. The recurrent pneumonia are among the main clinical manifestations of CVID,which appear between 20 and 40 years of age in most cases. The aim of this study was to analyse the possible relationship between environmental changes and the onset of pneumonia in patients with primary CVID.
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