Abstract

Pulmonary infection withPneumocystis cariniiis common among patients with acquired immunodeficiency syndrome (AIDS) and other immune system disorders.1Aerosolized pentamidine prophylaxis has been shown to prolong survival of patients with AIDS by preventing lung involvement.2Although uncommon, extrapulmonaryP cariniiinfection involving lymph nodes, spleen, adrenal glands, bone marrow, gastrointestinal tract, heart, and eyes has been documented.3,4Extrapulmonary pneumocystosis can occur in patients who receive aerosolized pentamidine prophylaxis since this manner of administration, unlike the conventional intravenous method, does not result in high serum or systemic drug levels.5Extrapulmonary pneumocystosis can be diagnosed if a biopsy of the involved organ is done appropriately. A 35-year-old man with a 2.5-year history of AIDS was admitted for fatigue and dyspnea. He had been treated forP cariniipneumonia with pentamidine and had been followed up with monthly aerosolized pentamidine prophylaxis. The patient's history included cytomegalovirus retinitis and

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