Abstract

International practice of immunization against pneumococcus in patients with systemic juvenile idiopathic arthritis (SJIA) receiving biological therapy is generalized in this review. High efficiency and safety of pneumococcal vaccines in children with SJIA is presented. Numerous researches show the adequate immune response after vaccination as well as alongside with genetically engineered biologic drugs therapy. Prevention of pneumococcal disease in patients with SJIA reduces the risk of development of pneumococcal diseases severe complications.

Highlights

  • International practice of immunization against pneumococcus in patients with systemic juvenile idiopathic arthritis (SJIA) receiving biological therapy is generalized in this review

  • Prevention of pneumococcal disease in patients with SJIA reduces the risk of development of pneumococcal diseases severe complications

  • Постепенное расширение охвата вакцинацией и даже неполный охват существенно снижают частоту инвазивных пневмококковых болезней во всех возрастных группах, а также способствуют формированию популяционного иммунитета, снижая уровень вирулентного бактерионосительства [5, 12, 17]

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Summary

Introduction

International practice of immunization against pneumococcus in patients with systemic juvenile idiopathic arthritis (SJIA) receiving biological therapy is generalized in this review. Что инфекции распространены у пациентов с ревматоидным артритом, и ревматологам необходимо вовремя выявлять факторы риска инфекционных осложнений [25]. В Российской Федерации до настоящего времени остро стоит проблема вакцинации хронически больных, а также детей, получающих иммуносупрессивную терапию или имеющих иммунодефицит, т.

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