Abstract
A pneumococcal disease outbreak caused by Streptococcus pneumoniae serotype 12F occurred in a state prison in Alabama, USA. Among 1,276 inmates, 40 cases were identified (3 confirmed, 2 probable, 35 suspected). Close living quarters, substance use, and underlying conditions likely contributed to disease risk. Prophylaxis for close contacts included azithromycin and 23-valent pneumococcal polysaccharide vaccine.
Highlights
A pneumococcal disease outbreak caused by Streptococcus pneumoniae serotype 12F occurred in a state prison in Alabama, USA
Probable cases were defined as suspected cases with radiographicconfirmed pneumonia, clinical sepsis, or cerebrospinal fluid analysis suggestive of bacterial meningitis with unknown etiology
We performed pneumococcal serotyping on nasopharyngeal swab specimens from which S. pneumoniae was isolated
Summary
This investigation highlights the outbreak potential of S. pneumoniae and demonstrates that correctional facilities remain at risk for pneumococcal outbreaks after PCV introduction in the United States. Epidemic curve of identified cases among inmates in study of pneumococcal disease outbreak at a state prison, Alabama, USA, September 1–October 10, 2018. Date of first symptom onset is shown. Healthcare unit visit date was used when symptom onset date was not known. Two suspected cases without a clear onset date were excluded from this graph
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