Pneumococcal Disease and HIV Infection

Abstract

Letters1 March 1993Pneumococcal Disease and HIV InfectionEdward H. Janoff, MDEdward H. Janoff, MDSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-118-5-199303010-00015 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail IN RESPONSE:The important work of Gilks suggests that the epidemiology and clinical spectrum of pneumococcal disease in HIV-infected patients is strikingly similar in the United States and Kenya. In both locations, HIV-infected patients comprise a significant proportion of patients with pneumococcal bacteremia, and Streptococcus pneumoniae is among the most common causes of bacteremia and pneumonia in patients with HIV. Moreover, rates of recurrent disease (relapse or reinfection) may be high, whereas mortality is often lower than among bacteremic, HIV-seronegative patients. Delineation of associated risk factors in Africa such as sickle cell disease, malnutrition, or malaria would be of interest. ...