PMO-134 Basal cell adhesion molecule and b1-integrins regulate the adhesion of ES cell-derived hepatocye-like cells to extracellular matrix and hepatic sinusoidal cells

N J Davies,P F Lalor,D H Adams,H S Dawes,D C Hay,P N Newsome,D W Blakeway

doi:10.1136/gutjnl-2012-302514b.134

PMO-134 Basal cell adhesion molecule and b1-integrins regulate the adhesion of ES cell-derived hepatocye-like cells to extracellular matrix and hepatic sinusoidal cells

N J Davies, P F Lalor + Show 5 more

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https://doi.org/10.1136/gutjnl-2012-302514b.134

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Journal: Gut

Publication Date: May 28, 2012

Affiliation: NIHR Birmingham Liver Biomedical Research Unit, University of Birmingham

#Embryonic Stem Cell-derived Hepatocyte-like Cells #Adhesion Molecule + Show 8 more

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Abstract

IntroductionCellular transplantation is an alternative to liver transplantation, however provision of primary human hepatocytes is limited. Human embryonic stem cell-derived hepatocyte-like cells (ES-HLCs) represent a renewable source of functional hepatocytes....

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