PM300 Type of Coronary Artery lesions and The incidence of Total Occlusion in Metabolic Syndrome Patients

Abstract

Introduction: The Constellation of metabolic abnormalities including centrally distributed obesity, decreased high-density lipoprotein, elevated triglycerides, elevated blood pressure, and hyperglycaemia are known as the metabolic syndrome. Metabolic syndrome amplifies and accelerates the risk of atherosclerosis. Coronary lesions were divided into type A,B,C, based on AHA Classification. This classification is useful to predict successful rate of coronary intervention as well as risk stratification for procedural complication and inhospital cardiovascular event. Other studies showed that severity of coronary lesions associated with long-term outcome. Objectives: To investigate type of coronary lesions and incidence of total occlusion in patients with metabolic syndrome. Methods: A Total 129 consecutive patients with or without metabolic syndrome who underwent coronary angiography were enrolled at January until September 2013. Patients categorized as having metabolic syndrome when they met the NCEP ATPIII definition for Asian Population. Results: From 129 patients, 81 (62%) met the criteria of metabolic syndrome. In patients with metabolic syndrome, it was found that coronary lesions type A, B, and C were 9,9%, 30,8%, and 59,2% respectively. 34,5% of patients with Type C lesions were total occlusion. In non-metabolic syndrome patients, It was found that non significant coronary lession, Type A, B, and C, were 18,7%, 43,7%, 33,3%, and 4,2%, respectively. No total oclussion lesion was found in non metabolic syndrome patients. It was a significant difference in coronary lesions severity and incidence of total occlusion between two groups (p <0.001). Conclusion: Metabolic syndrome was associated with the worse coronary lesions type and increased incidence of total occlusion. Disclosure of Interest: None Declared