Abstract
Plummer-Vinson also known as sideropenic dysphagia is a disease that is characterized by classical triad of iron deficiency anemia, dysphagia and esophageal web. It is known to mostly affect white female mainly, but cases have been reported from other ethnic group in the literature. Treatment is very promising especially when it is not associated with carcinoma. DOI: http://dx.doi.org/10.3126/jnps.v31i3.4259 J Nep Paedtr Soc 2011;31(3): 254-256
Highlights
Plummer-Vinson Syndrome (PVS) was first described by Patterson and Kelly in 19191
Symptoms resulting from anemia such as pallor, fatigue and weakness may dominate the clinical picture, in our case patient had suffered from dysphagia and pain abdomen
The pathogenesis of this syndrome is not exactly understood but the most probable mechanism is iron deficiency[9]. The other factors, such as genetic predisposition, malnutrition and autoimmunity have not been proven to play an exact role in the pathogenesis of the syndrome, celiac disease, thyroid disease and rheumatoid arthritis have been reported with PVS1,10,11
Summary
Plummer-Vinson Syndrome (PVS) was first described by Patterson and Kelly in 19191. It consists of the triad of dysphagia, iron deficiency anemia and upper esophageal web(s). Along with it, it consists of atrophic oral mucosa, cracks or fissure at the corners of the mouth along with painful tongue, koilonychia or nails that are brittle and break [2,3]. Dysphagia is usually progressive over years, and limited to solids. Most of the patients affected are middle aged women and it is very rare in childhood[2,3]
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
