Abstract
Antibiotics have been the mainstay of treatment for a variety of infectious diseases such as pneumonia. Due to the increasing incidence of antimicrobial resistance, we are at risk of returning to the pre-antibiotic era, and the need to develop new drugs rapidly is becoming more urgent. A new computational method could provide quantitative insights to the interaction between an antimicrobial agent and a pathogen, which would facilitate new agent development by rationally guiding selection of dosing regimens. (See Tam and Nikolau, doi:10.1371/journal.pcbi.1001043.) Image Credit: Thomas Shea, University of Houston Cullen College of Engineering
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