Abstract
A summary of the two types of HIV adaptations predicted by a new statistical model of HIV evolution is shown. The two types of adaptation are to (i) immune system molecules (e.g., B57) shown on the outside and (ii) other positions in HIV. The dense network implies that the same adaptations consistently arise in certain environments and may point to weak spots in the viral genome that will be important for vaccine and drug design (see Carlson et al., doi:10.1371/journal.pcbi.1000225). Image Credit: Jonathan Carlson and David Heckerman (Microsoft Research).
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