Abstract
biology. Indeed, studies of this phenomenon from a therapeutic point of view contributed to the development of antibiotics. More recently, direct bacterial interference, rather than the use of an active microbial product, has been employed in situations in which repeated therapy with antibiotics has been ineffective. The most notable use of interference has been with staphylococci; an avirulent strain has been inoculated to terminate epidemics of staphylococcal infection in newborn infants [1, 2] and to stop repeated infections in individuals [3, 4] or to halt the spread of intrafamilial infections [5, 6]. Comparable studies have not been conducted in human pyelonephritis, but the question frequently arises whether mixed infections exist when several bacteria are isolated from the urine or appear sequentially with or without therapy. If mixed infections do exist, the role of bacterial interference in maintaining relationships between different bacteria may need study. The availability of a model of experimental pyelonephritis in the rat has permitted study of bacterial interference in renal disease. Streptococ-
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
