Abstract
Intravenous drug abuse related plexogenic pulmonary hypertension unassociated with recurrent thromboembolism or foreign-body granulomatous disease of the lung has not been previously reported. Herein, we describe the occurrence of fatal plexogenic pulmonary hypertension in a 33-year-old Hispanic woman who had a history of chronic intravenous drug abuse. In the absence of other known causes, cocaine-induced chronic vasoconstriction was the most probable pathogenic mechanism of plexogenic pulmonary hypertension in this patient.
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