Abstract

Introduction: Pleuropulmonary blastoma (PPB) is a dysontogenetic neoplasm of childhood that appears as a pulmonary and/or pleural­based mass. PPB is of three types: cystic (type I), mixed (type II), or solid (type III). It is rarely observed in adults with only a few cases reported in literature. Case Report: We present a case of a 30­year­old male with complaints of chest pain, dyspnea and low grade fever. His computed tompgraphy scan of chest showed three multicystic lesions in right hemithorax. Cytomorphological examination of imprint smears of biopsies taken from the masses suggested malignant lesion and on histological examination, diagnosis of pleuropulmonary blastoma type II was made. Conclusion: Pleuropulmonary blastoma is a rare and aggressive malignant tumor of childhood. Familial disposition and association of PPB tumor with other childhood malignancies has been suggested in literature. Pathologically, the tumor tissue is composed of primitive blastemal cells with focal areas of malignant mesenchyme. Therapy should include surgical tumor resection and subsequent chemotherapy and radiotherapy. PPB is very rare tumor in adults and presentation as multiple lesions in one sided hemithorax has not been reported. PPB should be considered in the clinical and radiographic differential diagnosis of multicystic lesions, even when the patient is a young adult.

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