Pleural space infection bacteriology and clinical, laboratory, and physical outcomes

Abstract

Introduction and Objectives: Even with the development of powerful medicines, bacterial pneumonia remains a leading cause of death and disability. The goal of this article is to discuss the bacteriology of pleural space infection and to identify the parameters that would predict infection outcome in different types of parapneumonic effusion.Materials and Methods: Observational study of patients diagnosed with simple, difficult, or complex parapneumonic effusion who were admitted at the Department of Respiratory Medicine, Mamata Medical College, Khammam, Telangana, India, between March 2019 to September 2019. Gram staining and culture growth of pleural fluid was examined to characterised the bacteria that cause pleural space infection. Multiple logistic regressions were used to statistically analyse the data and draw comparisons between the two outcomes.Results: Multiple logistic regression models and a univariate model were utilised. Comparable gram-positive and gram-negative bacterial growth was seen in this study of pleural space infections. pH, loculation, positive stain, culture, fever, and serum albumin were all statistically significant in independent analyses. Tube thoracostomy success or failure was significantly predicted by PH, loculation, and serum albumin in a multivariate analysis.Conclusion: Predictive indicators for the prognosis of difficult and complex parapneumonic effusion included pleural fluid pH, loculation, and serum albumin in a multivariate analysis. They may be put to use in sending patients on to more permanent care.